Journal article
A conceptual framework to assess the risks of human disease following exposure to pathogens
Risk analysis, v 16(6), pp 841-848
01 Dec 1996
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Currently, risk assessments of the potential human health effects associated with exposure to pathogens are utilizing the conceptual framework that was developed to assess risks associated with chemical exposures. However, the applicability of the chemical framework is problematic due to many issues that art: unique to assessing risks associated with pathogens. These include, but are not limited to, an assessment of pathogen/host interactions, consideration of secondary spread, consideration of short- and long-term immunity, and an assessment of conditions that allow the microorganism to propagate. To address this concern, a working group was convened to develop a conceptual framework to assess the risks of human disease associated with exposure to pathogenic microorganisms. The framework that was developed consists of three phases: problem formulation, analysis (which includes characterization of exposure and human health effects), and risk characterization. The framework emphasizes the dynamic and iterative nature of the risk assessment process, and allows wide latitude for planning and conducting risk assessments in diverse situations, each based on the common principles discussed in the framework.
Metrics
Details
- Title
- A conceptual framework to assess the risks of human disease following exposure to pathogens
- Creators
- G Craun - United States Environmental Protection AgencyA Dufour - United States Environmental Protection AgencyJ EisenbergJ Foran - The University of Texas Health Science Center at San AntonioC Gauntt - The University of Texas at San AntonioC Gerba - University of ArizonaC Haas - Centers for Disease Control and PreventionA Highsmith - Centers for Disease Control and PreventionR Irbe - Centers for Dis. Contr./Prev.P Julkunen - Coca ColaD Juranek - University of Maryland, BaltimoreM LeChevallier - United States Environmental Protection AgencyM Levine - United States Environmental Protection AgencyB Macler - University of North CarolinaP Murphy - United States Environmental Protection AgencyP Payment - United States Environmental Protection AgencyF Pfaender - Amer. Water Wk. Assoc. Res. Found.S Regli - United States Environmental Protection AgencyA Roberson - United States Environmental Protection AgencyJ Rose - U.S. Environmental Protection AgencyS Schaub - University of California, BerkeleyG Schiff - Smith FamilyJ Seed - University of California, BerkeleyC Smith - University of California, BerkeleyM Sobsey - Environmental Science and EngineeringR Spear - Smith FamilyWalls
- Publication Details
- Risk analysis, v 16(6), pp 841-848
- Publisher
- Wiley
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Civil, Architectural, and Environmental Engineering
- Web of Science ID
- WOS:A1996VY70300013
- Scopus ID
- 2-s2.0-12644265332
- Other Identifier
- 991019170451804721
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InCites Highlights
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Mathematics, Interdisciplinary Applications
- Public, Environmental & Occupational Health
- Social Sciences, Mathematical Methods