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A graphical tool to evaluate temporal coverage of occupational history by exposure measurements
Journal article   Open access   Peer reviewed

A graphical tool to evaluate temporal coverage of occupational history by exposure measurements

Jelle Vlaanderen, Wouter Fransman, Brian Miller, Igor Burstyn, Dick Heederik, Fintan Hurley, Roel Vermeulen and Hans Kromhout
Occupational and environmental medicine (London, England), v 67(9), pp 636-638
Sep 2010
PMID: 20798029
url
https://doi.org/10.1136/oem.2009.053421View
Published, Version of Record (VoR) Open

Abstract

IntroductionIn occupational epidemiology, differences in the temporal coverage of the exposure history by available exposure measurement data may affect the uncertainty of exposure estimates. In the reporting of results of studies, greater attention should be paid to the extent to which exposure assessments require extrapolation outside the timeframe for which exposure measurements are available. We propose a simple graphical method that can be used to visualise the temporal coverage of exposure history with exposure measurements and the extent of temporal extrapolation needed.MethodsWe construct a graph that displays the accumulated work history years for which exposure had to be assessed in each calendar year. Years for which exposure measurements were available are shaded. The proportion of work history years covered by exposure measurements and the proportion of work history years accrued before the first measurements are summarised. When available, the actual number of measurements available in each calendar year is shown.ResultsWe demonstrate the application of the graphical tool in three nested case–control studies that reported on leukaemia in relation to low-level benzene exposures in the petroleum industry. Considerable differences in temporal coverage between the studies were illustrated, which may have resulted in differences in the reliability of the retrospective exposure estimates derived for these studies.ConclusionWe introduce a graphical tool for visualising the temporal coverage by available exposure measurement data in epidemiological studies and encourage others to use similar graphs to derive and share better qualitative insights into the uncertainty in exposure assessment.

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Collaboration types
Domestic collaboration
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Web of Science research areas
Public, Environmental & Occupational Health
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