Journal article
A highly enantioselective synthesis of (R)- and (S)-5,7-odimethyleucomol
Tetrahedron letters, v 31(47), pp 6823-6826
1990
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Both (R)- and (S)-5,7-O-dimethyleucomol
1b (R = Me) were synthesized in 57% overall yield in >96% enantiomeric excess. The key step involves the enantioselective α hydroxylation of the lithium enolate of
8 by readily available (+)- and (−)-[(8,8-dimethoxycamphoryl)sulfonyl]oxaziridine
9c.
Both (R)- and (S)-5,7-O-dimethyleucomol
1b were synthesized in 57% overall yield in >96% ee via the enantioselective α-hydroxylation of the lithium enolate of
8 by (+)- and (−)-
9c.
Metrics
Details
- Title
- A highly enantioselective synthesis of (R)- and (S)-5,7-odimethyleucomol
- Creators
- Franklin A. Davis - Drexel UniversityBang-Chi Chen - Drexel University
- Publication Details
- Tetrahedron letters, v 31(47), pp 6823-6826
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1990EJ09600020
- Scopus ID
- 2-s2.0-0025049743
- Other Identifier
- 991019173663404721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Chemistry, Organic