Journal article
A new method of evaluating antitumor activity from measured tumor volumes
Contemporary clinical trials, v 27(3), pp 269-273
2006
PMID: 16388989
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
In studies of antitumor activity, measurement of tumor growth delay is commonly used to evaluate treatment effects. However, this measurement sometimes provides no information. We propose an approach for comparing tumor response by using nonparametric regression. In a xenograft model, we found that a significant difference between two treatment effects was undetectable by comparison of tumor growth delays. The results of our finding suggest that measurements used to evaluate the treatment effects should be carefully selected in analyses of antitumor activity.
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Details
- Title
- A new method of evaluating antitumor activity from measured tumor volumes
- Creators
- Hua Liang - University of Rochester Medical Center
- Publication Details
- Contemporary clinical trials, v 27(3), pp 269-273
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000237791900007
- Scopus ID
- 2-s2.0-33646189914
- Other Identifier
- 991019320711104721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Medicine, Research & Experimental
- Pharmacology & Pharmacy