Journal article
A novel electrospinning setup for the fabrication of thickness-controllable 3D scaffolds with an ordered nanofibrous structure
Materials letters, v 160, pp 343-346
01 Dec 2015
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Abstract
Electrospinning is a popular nanotechnology used to produce fibrous scaffolds from a wide range of materials. For tissue regeneration and bioengineering applications, there is a growing interest in fabricating tailored 3D scaffolds with a complex tissue-like structure, i.e., nanometer diameter, aligned fibers and controllable thickness that may be suitable for specific organs and tissues. However, conventional electrospinning techniques can only produce either 2D aligned nanofibrous structures with limited thickness or 3D fibrous scaffolds with disordered fibrous structures. In this study, a novel electrospinning setup using a parallel double thin plate collector device and a separate fiber removal device was developed to generate 3D electrospun scaffolds with aligned nanofibers and controllable thickness. As a demonstration, the formation mechanism of the ordered fibrous structure was analyzed, and polyvinyl alcohol (PVA) was processed into fibrous scaffolds. The nanofibrous membranes possessed a high alignment degree with approximately 76% of the fibers within +/-5 degrees and tailored thicknesses from 69.6 to 1144.9 mu m. Crown Copyright (C) 2015 Published by Elsevier B.V. All rights reserved.
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Details
- Title
- A novel electrospinning setup for the fabrication of thickness-controllable 3D scaffolds with an ordered nanofibrous structure
- Creators
- Shengli Mi - Tsinghua UniversityBin Kong - Tsinghua UniversityZhengjie Wu - Tsinghua UniversityWei Sun - Tsinghua UniversityYuanyuan Xu - Tsinghua UniversityXin Su - Tsinghua University
- Publication Details
- Materials letters, v 160, pp 343-346
- Publisher
- Elsevier
- Number of pages
- 4
- Grant note
- 31200724 / National Natural Science Foundation of China; National Natural Science Foundation of China (NSFC) JCYJ 20140509172959988 / Projects of Basic Research of Shenzhen 2014M560986 / China Postdoctoral Science Foundation JC20140005 / Cross Scientific Research Innovation Fund of Graduate School at Shenzhen of Tsinghua University KQCX20130628155525051 / Shenzhen Peacock Plan
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000364880300087
- Scopus ID
- 2-s2.0-84938781685
- Other Identifier
- 991019167651204721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Materials Science, Multidisciplinary
- Physics, Applied