Journal article
A novel host-adapted strain of Salmonella Typhimurium causes renal disease in olive ridley turtles (Lepidochelys olivacea) in the Pacific
Scientific reports, v 9(Jun (E-published)), pp 9313-13
27 Jun 2019
PMID: 31249336
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Salmonella
spp. are frequently shed by wildlife including turtles, but
S. enterica
subsp.
enterica
serovar Typhimurium or lesions associated with
Salmonella
are rare in turtles. Between 1996 and 2016, we necropsied 127 apparently healthy pelagic olive ridley turtles (Lepidochelys olivacea) that died from drowning bycatch in fisheries and 44 live or freshly dead stranded turtles from the west coast of North and Central America and Hawaii. Seven percent (9/127) of pelagic and 47% (21/44) of stranded turtles had renal granulomas associated with
S
. Typhimurium. Stranded animals were 12 times more likely than pelagic animals to have
Salmonella
-induced nephritis suggesting that
Salmonella
may have been a contributing cause of stranding.
S
. Typhimurium was the only
Salmonella
serovar detected in
L. olivacea
, and phylogenetic analysis from whole genome sequencing showed that the isolates from
L. olivacea
formed a single clade distinct from other
S
. Typhimurium. Molecular clock analysis revealed that this novel clade may have originated as recently as a few decades ago. The phylogenetic lineage leading to this group is enriched for non-synonymous changes within the genomic area of Salmonella pathogenicity island 1 suggesting that these genes are important for host adaptation.
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Details
- Title
- A novel host-adapted strain of Salmonella Typhimurium causes renal disease in olive ridley turtles (Lepidochelys olivacea) in the Pacific
- Creators
- Thierry M. Work - National Wildlife Health CenterJulie Dagenais - National Wildlife Health CenterBrian A. Stacy - University of FloridaJason T. Ladner - Northern Arizona UniversityJeffrey M. Lorch - National Wildlife Health CenterGeorge H. Balazs - Golden Honu Services of Oceania, Honolulu, Hawaii 96825 United States of AmericaElías Barquero-Calvo - Universidad NacionalBrenda M. Berlowski-Zier - National Wildlife Health CenterRenee Breeden - National Wildlife Health CenterNatalia Corrales-Gómez - Universidad NacionalRocio Gonzalez-Barrientos - Ministry of Agriculture and LivestockHeather S. Harris - NOAA National Marine Fisheries ServiceGabriela Hernández-Mora - Ministry of Agriculture and LivestockÁngel Herrera-Ulloa - Ministry of Agriculture and LivestockShoreh Hesami - University of FloridaT. Todd Jones - Honolulu, Hawaii 96818 United States of AmericaJuan Alberto Morales - Universidad NacionalTerry M. Norton - Georgia Sea Turtle Center/Jekyll Island Authority, Jekyll Island, Georgia, 31527 United States of AmericaRobert A. Rameyer - National Wildlife Health CenterDaniel R. Taylor - National Wildlife Health CenterThomas B. Waltzek - University of Florida
- Publication Details
- Scientific reports, v 9(Jun (E-published)), pp 9313-13
- Publisher
- Nature Publishing Group UK
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000472999700005
- Scopus ID
- 2-s2.0-85068067527
- Other Identifier
- 991021838287404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Microbiology