Journal article
A novel reflectance-based aptasensor using gold nanoparticles for the detection of oxytetracycline
Analyst (London), v 140(19), pp 6671-6675
2015
PMID: 26334055
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Abstract
We present a novel reflectance-based colorimetric aptasensor using gold nanoparticles for the detection of oxytetracycline for the first time. It was found that the reflectance-based measurement at two wavelengths (650 and 520 nm) can generate more stable and sensitive signals than absorbance-based sensors to determine the aggregation of AuNPs, even at high AuNP concentrations. One of the most common antibacterial agents, oxytetracycline (OTC), was detected at concentrations as low as 1 nM in both buffer solution and tap water, which was 25-fold more sensitive, compared to the previous absorbance-based colorimetric aptasensors. This reflectance-based colorimetric aptasensor using gold nanoparticles is considered to be a better platform for portable sensing of small molecules using aptamers.
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Details
- Title
- A novel reflectance-based aptasensor using gold nanoparticles for the detection of oxytetracycline
- Creators
- Ho Bin Seo - Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of KoreaYoung Seop Kwon - Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of KoreaJi-eun Lee - Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of KoreaDavid Cullen - Cranfield Biotechnology Centre, Institute of BioScience and Technology, Cranfield University at Silsoe, Silsoe, UKHongseok (Moses) Noh - Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, USAMan Bock Gu - Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of Korea
- Publication Details
- Analyst (London), v 140(19), pp 6671-6675
- Publisher
- Royal Society of Chemistry
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000361379100031
- Scopus ID
- 2-s2.0-84941703021
- Other Identifier
- 991014878368704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Chemistry, Analytical