Journal article
A protective monoclonal antibody recognizes a variant-specific epitope in the precursor of the major merozoite surface antigen of rodent malarial parasite Plasmodium yoelii
The Journal of immunology (1950), v 142(8), pp 2835-2840
01 Jan 1989
PMID: 2467942
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Abstract
The precursor of the major merozoite surface Ag (PMMSA) represents one of the principal molecules of the erythrocytic stages of malarial parasites. Previously the authors reported that mAb 302 recognizing the 230-kDa PMMSA of Plasmodium yoelii provided passive protection to mice challenged with this parasite. They now report that the protective capacity of mAb 302 is variant specific, affording protection against infection with only three of five P. yoelii lines.
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Details
- Title
- A protective monoclonal antibody recognizes a variant-specific epitope in the precursor of the major merozoite surface antigen of rodent malarial parasite Plasmodium yoelii
- Creators
- J M BurnsL A ParkeT DalyL A CavaciniW WeidanzC A Long
- Publication Details
- The Journal of immunology (1950), v 142(8), pp 2835-2840
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:A1989U213600037
- Scopus ID
- 2-s2.0-0024507607
- Other Identifier
- 991019183920704721
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- Web of Science research areas
- Immunology