Journal article
A randomized trial of prescribed patching regimens for treatment of severe amblyopia in children
Ophthalmology (Rochester, Minn.), v 110(11), pp 2075-2087
Nov 2003
PMID: 14597512
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
OBJECTIVETo compare full-time patching (all hours or all but 1 hour per day) to 6 hours of patching per day, as prescribed treatments for severe amblyopia in children younger than 7 years.DESIGNProspective, randomized multicenter clinical trial (32 sites).PARTICIPANTSOne hundred seventy-five children younger than 7 years with amblyopia in the range of 20/100 to 20/400.INTERVENTIONRandomization either to full-time patching or to 6 hours of patching per day, each combined with at least 1 hour of near-visual activities during patching.MAIN OUTCOME MEASUREVisual acuity in the amblyopic eye after 4 months.RESULTSVisual acuity in the amblyopic eye improved a similar amount in both groups. The improvement in the amblyopic eye acuity from baseline to 4 months averaged 4.8 lines in the 6-hour group and 4.7 lines in the full-time group (P = 0.45).CONCLUSIONSix hours of prescribed daily patching produces an improvement in visual acuity that is of similar magnitude to the improvement produced by prescribed full-time patching in treating severe amblyopia in children 3 to less than 7 years of age.
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Details
- Title
- A randomized trial of prescribed patching regimens for treatment of severe amblyopia in children
- Creators
- Jonathan M HolmesRaymond T KrakerRoy W BeckEileen E BirchSusan A CotterDonald F EverettRichard W HertleGraham E QuinnMichael X RepkaMitchell M ScheimanDavid K WallaceThe Pediatric Eye Disease Investigator Group
- Publication Details
- Ophthalmology (Rochester, Minn.), v 110(11), pp 2075-2087
- Publisher
- ELSEVIER SCIENCE INC; NEW YORK
- Number of pages
- 13
- Grant note
- NEI NIH HHS: U10 EY011751, EY11751
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000186252900002
- Scopus ID
- 2-s2.0-0242286195
- Other Identifier
- 991021900187104721
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- Web of Science research areas
- Ophthalmology