Journal article
A statistical analysis of human talar shape and bone density distribution
Journal of orthopaedic research, Vol.42(8), pp.1780-1790
Aug 2024
PMID: 38483072
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The shape of the talus, its internal structure, and its mechanical properties are important in determining talar behavior during loading, which may be significant for the design of surgical tools and implants. Although recent studies using statistical shape modeling have described quantitative talar external shape variation, no similar quantitative study exists to describe the density distribution of internal talar structure. The goal of this study is to quantify statistical variation in talar shape and density to benefit the design of talar implants. To this end, weight-bearing computed tomography (CT) scans of the ankle were collected in neutral, bilateral standing posture, and three-dimensional models were generated for each talus. Local density derived from the Hounsfield unit of each CT voxel was extracted. A weighted spherical harmonic analysis was performed to quantify the talar external shape. One hundred and seventy-nine volumes of interest were placed in the same relative position within each talus to quantify the talar density. Additionally, a finite element analysis (FEA) was conducted on a talus with both heterogeneous and homogeneous material properties to observe the effect of these properties on the stress and strain response. Significant differences were found in the talar density in sex and age, as well as in the stress and strain response between homogeneous and heterogeneous FEA. These differences show the importance of considering heterogeneity when examining the load response of tarsal bones.
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Details
- Title
- A statistical analysis of human talar shape and bone density distribution
- Creators
- Jordan Stolle - Drexel UniversityChristine M Harper - Cooper Medical School of Rowan UniversityKristyn K Voegele - Rowan UniversityAhmad R Najafi - Drexel UniversityMehrangiz Taheri - Drexel UniversityJoshua MacBain - Drexel UniversitySorin Siegler - Drexel University
- Publication Details
- Journal of orthopaedic research, Vol.42(8), pp.1780-1790
- Publisher
- Wiley
- Number of pages
- 11
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:001184661900001
- Scopus ID
- 2-s2.0-85188234872
- Other Identifier
- 991021863173004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Orthopedics