Journal article
A study on lyophilization injection of cucurbitacin polylactic acid nanoparticles
Zhongguo zhongyao zazhi, v 26(5), pp 315-317
01 May 2001
PMID: 12528519
Abstract
OBJECTIVETo prepare stable and redispersable Lyophilization injection of cucurbitacin polylactic acid nanoparticles(Cu-PLA-NP).METHODAn optimal supporting agent was chosen to prepare the Cu-PLA-NP lyophilization injection. The physical and chemical properties of the injection were evaluated.RESULTSThe shape, diameters, association ratio, drug loading and pH of Cu-PLA-NP colloidal solution and lyophilization injection were not changed. The content of water consisted with the requirement of lyophilization injection. The critical relative humidity was 69.52%. The stability was good.CONCLUSIONIt is practicable to prepare Cu-PLA-NP lyophilization injection with proper formulas and preparation processes.
Metrics
4 Record Views
Details
- Title
- A study on lyophilization injection of cucurbitacin polylactic acid nanoparticles
- Creators
- C Y LiS X Hou
- Publication Details
- Zhongguo zhongyao zazhi, v 26(5), pp 315-317
- Resource Type
- Journal article
- Language
- Chinese
- Academic Unit
- Materials Science and Engineering
- Scopus ID
- 2-s2.0-0035354007
- Other Identifier
- 991019196537004721