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ADDITION OF DIMETHYLOXOSULFONIUM METHYLIDE TO ENANTIOMERICALLY PURE SULFINIMINES - ASYMMETRIC-SYNTHESIS OF 2-SUBSTITUTED AZIRIDINES
Journal article   Peer reviewed

ADDITION OF DIMETHYLOXOSULFONIUM METHYLIDE TO ENANTIOMERICALLY PURE SULFINIMINES - ASYMMETRIC-SYNTHESIS OF 2-SUBSTITUTED AZIRIDINES

F A Davis, P Zhou, C H Liang and R E Reddy
Tetrahedron: asymmetry, v 6(7), pp 1511-1514
01 Jul 1995

Abstract

Chemistry Chemistry, Inorganic & Nuclear Chemistry, Organic Chemistry, Physical Physical Sciences Science & Technology
Diastereoselective addition of dimethyloxosulfonium methylide to chiral nonracemic pure sulfinimines 1 affords N-sulfinyl aziridines 3 in 58-70% de which are readily separated. The N-sulfinyl auxiliary in 3 was removed, without ring-opening, by treatment with MeLi.

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Web of Science research areas
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
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