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ADDRESSING DEMENTIA CLINICAL SYMPTOMS USING NONPHARMACOLOGICAL STRATEGIES: WHAT WORKS AND FOR WHOM?
Journal article   Open access   Peer reviewed

ADDRESSING DEMENTIA CLINICAL SYMPTOMS USING NONPHARMACOLOGICAL STRATEGIES: WHAT WORKS AND FOR WHOM?

Laura N Gitlin, Katherine A Marx, Catherine Verrier Piersol, Nancy A Hodgson, Jin Huang, David Roth and Constantine G Lyketsos
Innovation in aging, v 3(Suppl 1), pp S182-S182
08 Nov 2019
DOI: https://doi.org/10.1093/geroni/igz038.650
url
https://academic.oup.com/innovateage/article-pdf/3/Supplement_1/S182/33004992/igz038.650.pdfView
Published, Version of Record (VoR) Open
url
https://doi.org/10.1093/geroni/igz038.650View
Published, Version of Record (VoR) Open

Abstract

Session 1000 (Symposium)
People living with dementia experience behavioral symptoms and functional decline and their caregivers (CG), reduced wellbeing. In an RCT (N=250 dyads), we tested whether tailoring activities to interests/abilities and providing CGs with instruction in their use (Tailored Activity Program, TAP) reduced clinically significant agitation/aggression (main outcome), functional decline and improved CG wellbeing (secondary outcomes) compared to CG education/support alone; with both groups receiving 8-sessions over 3-months. At 3-months,TAP had no effects on agitation/aggression compared to CG education/support but reduced functional decline (p=0.03), improved CG wellbeing (p=0.01) and confidence using activities (p=0.02). In secondary analyses, black vs. white CGs reported reduced agitation/aggression (p=0.01); female CGs reported reduced burden with TAP whereas male CGs reported reduced burden from education/support (p=0.04); spouses vs. non-spouses reported slower functional decline in participants (p=0.01). This trial suggests outcomes vary by subgroups. Different nonpharmacological approaches are needed for specific clinical characteristics: one size will not fit all.

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