Journal article
Abstract MP50: Neighborhood Social And Economic Environment And Heart Failure Risk Among Adults With & Without Diabetes: The Reasons For Geographic And Racial Differences In Stroke (regards) Study
Circulation (New York, N.Y.), v 143(Suppl_1), pAMP50
25 May 2021
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Abstract only
Background:
Heart failure (HF) mortality rates have been increasing since 2011. Individual-level education and occupation have been inversely associated with HF mortality among those with diabetes mellitus (DM) but not among those without DM. However, less is known about the association between neighborhood social and economic environment (NSEE) and HF risk and whether this association varies by DM status.
Methods:
This study included 21,244 Black and White adults age >=45 years at baseline (2003-07) from the REGARDS Study. NSEE quartiles were created using z-scores based on 6 census tract variables from year 2000 (% <high school education, % unemployed, % household with <$30,000, % living in poverty, % on public assistance, % without car). Incident HF events (fatal or non-fatal) were adjudicated based on hospitalization with HF signs and symptoms, supportive imaging or biomarkers. Diabetes was defined as fasting glucose >=126 mg/dL or random glucose >=200 mg/dL or use of diabetes medications. Cox proportional hazards regression was used to obtain hazard ratios (95% CI) with HF follow-up through 2016.
Results:
Mean age was 65 years, 54% were women, 61% were White and 18% had prevalent DM at baseline. During a median 10.1 years, 829 incident HF events occurred. Among adults with DM, neighborhood disadvantage was associated with an increased HF risk , but this association was not statistically significant (Table). Among adults without DM, the risk of HF was higher for participants living in any neighborhood that was not the most advantaged, and the magnitude of association was smiliar across NSEE quartiles.
Conclusion:
Adults living in disadvantaged neighborhoods had a higher risk of HF, particularly among those without DM. Addressing neighborhood social and economic conditions may be important for HF prevention.
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Details
- Title
- Abstract MP50: Neighborhood Social And Economic Environment And Heart Failure Risk Among Adults With & Without Diabetes: The Reasons For Geographic And Racial Differences In Stroke (regards) Study
- Creators
- Gargya Malla - University of Alabama at BirminghamAndrea Cherrington - University of Alabama at BirminghamMonika M Safford - Cornell UniversityParag Goyal - Cornell UniversityDoyle M Cummings - East Carolina UniversityTara McAlexander - Drexel UniversityShanika De Silva - Drexel UniversitySuzanne E Judd - Universidade AbertaBertha Hidalgo - University of Alabama at BirminghamEmily B Levitan - University of Alabama at BirminghamApril P Carson - University of Alabama at Birmingham
- Publication Details
- Circulation (New York, N.Y.), v 143(Suppl_1), pAMP50
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000689539900121
- Other Identifier
- 991021463585004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Peripheral Vascular Disease