Journal article
Abstract P488: Discrimination and Hypertension Risk Among African Americans in The Jackson Heart Study
Circulation (New York, N.Y.), v 141(Suppl_1)
03 Mar 2020
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background:
African Americans have a higher risk for hypertension compared to other racial or ethnic groups in the United States. One possible explanation for this health disparity is perceived discrimination. Few studies have prospectively examined the association between discrimination and the incidence of hypertension.
Methods:
We examined the associations of everyday, lifetime, and stress from lifetime discrimination with incident hypertension and whether these associations differed by sex, discrimination attribution (i.e. the main reason for the discrimination event), and coping responses to discrimination among African Americans enrolled in the Jackson Heart Study. Discrimination was self-reported by 1845 African Americans aged 21 to 85 years without hypertension at baseline (2000-2004). Participants completed two follow-up study visits from 2005-2008 and 2009-2013. We used interval-censored Cox regression to estimate associations of discrimination with incident hypertension (antihypertensive medication use; and/or systolic blood pressure ≥ 140 mm Hg and diastolic blood pressure ≥ 90 mm Hg at follow-up visits 2 or 3) after adjustment for confounding variables.
Results:
Overall, 52% (954 of 1845) of participants developed hypertension over the follow-up period. After adjustment for age, sex, education and hypertension risk factors (body mass index, alcohol use, smoking, diet and physical activity), medium versus low levels of lifetime discrimination (hazard ratio-HR: 1.45, 95% confidence interval-CI: 1.15-1.82) and high versus low levels of lifetime discrimination (HR: 1.35, CI: 1.08-1.68) were associated with a higher incidence of hypertension. High versus low stress from lifetime discrimination was associated with hypertension risk after adjustment for demographics (HR: 1.20, CI: 1.02-1.41), but the association was attenuated after adjustment for hypertension risk factors (HR: 1.14, CI: 0.97-1.35). Lifetime discrimination and stress from discrimination were associated with an increased hypertension risk among females, but not males. No interactions with age, attribution or coping were present for any type of discrimination.
Conclusions:
Findings from this study support an association between lifetime discrimination and incident hypertension in African Americans.
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Details
- Title
- Abstract P488: Discrimination and Hypertension Risk Among African Americans in The Jackson Heart Study
- Creators
- Allana T Forde - Drexel UniversityMario Sims - University of MississippiPaul Muntner - University of Alabama at BirminghamTené Lewis - Emory UniversityAmanda Onwuka - Nationwide Children's HospitalKari Moore - Drexel UniversityAna V Diez Roux - Drexel University
- Publication Details
- Circulation (New York, N.Y.), v 141(Suppl_1)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000589965800450
- Other Identifier
- 991019168312404721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Peripheral Vascular Disease