Journal article
Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline
Diagnostic microbiology and infectious disease, v 88(4), pp 365-367
01 Aug 2017
PMID: 28535946
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We examined the in vitro activity of minocycline against 103 Klebsiella pneumoniae carbapenemase (KPC)producing Enterobacteriaceae isolates and found approximately half had susceptible (26%) or intermediate (26%) MICs. For a subset of 35 isolates, susceptibility was highest to tigecycline (71% FDA vs. 20% EUCAST) followed by minocycline (14%) and then doxycycline (6%). (C) 2017 Elsevier Inc. All rights reserved.
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Details
- Title
- Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline
- Creators
- Alice Chen - Northeastern UniversityKenneth P. Smith - Beth Israel Deaconess Medical CenterBetsy A. Whitfield - Northeastern UniversityPaola C. Zucchi - Northeastern UniversityTodd M. Lasco - St. Luke's HospitalTiffany E. Bias - Hahnemann University HospitalJames E. Kirby - Beth Israel Deaconess Medical CenterElizabeth B. Hirsch - Beth Israel Deaconess Medical Center
- Publication Details
- Diagnostic microbiology and infectious disease, v 88(4), pp 365-367
- Publisher
- Elsevier
- Number of pages
- 3
- Grant note
- Northeastern University Advanced Undergraduate Research Award
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000406892700014
- Scopus ID
- 2-s2.0-85019900749
- Other Identifier
- 991019330804004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Infectious Diseases
- Microbiology