Journal article
Acute Respiratory Distress Syndrome
Critical care nursing quarterly, v 39(2), pp 190-195
01 Apr 2016
PMID: 26919679
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Acute respiratory distress syndrome (ARDS) is a serious inflammatory disorder with high mortality. Its main pathologic mechanism seems to result from increased alveolar permeability. Its definition has also changed since first being described according to the Berlin definition, which now classifies ARDS on a severity scale based on PaO2 (partial pressure of oxygen, arterial)/FIO2 (fraction of inspired oxygen) ratio. The cornerstone of therapy was found to be a low tidal volume strategy featuring volumes of 6 to 8 mL per kg of ideal body weight that has been shown to have decreased mortality as proven by the ARDSnet trials. There are other areas of treatment right now that include extracorporeal membrane oxygenation, as well for severe refractory hypoxemia. Other methods that include prone positioning for ventilation have also shown improvements in oxygenation. Positive end-expiratory pressure with lung recruitment maneuvers has also been found to be helpful. Other therapies that include vasodilators and neuromuscular agents are still being explored and need further studies to define their role in ARDS.
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Details
- Title
- Acute Respiratory Distress Syndrome
- Creators
- Suman Yadam - Allegheny Health NetworkEric Bihler - Allegheny Health NetworkMarvin Balaan - Allegheny Health Network
- Publication Details
- Critical care nursing quarterly, v 39(2), pp 190-195
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- General Internal Medicine
- Web of Science ID
- WOS:000382083600011
- Scopus ID
- 2-s2.0-84959889134
- Other Identifier
- 991022084054304721
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- Web of Science research areas
- Critical Care Medicine