Journal article
Acute bowel morbidity after prostate brachytherapy with cesium-131
Brachytherapy, v 10(1), pp 51-56
Jan 2011
PMID: 20797922
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The present study evaluates the severity and time to resolution of bowel symptoms in men undergoing prostate brachytherapy (PB) with cesium-131 ((131)Cs).
A longitudinal, prospective study of patients who had undergone PB with (131)Cs at a single institution was performed. All patients were asked to complete the Expanded Prostate Cancer Index Composite preoperatively and at 2 weeks and 1, 3, and 6 months postoperatively. Outcomes were analyzed using descriptive statistics and Student's t test.
The first 142 patients to have undergone PB with (131)Cs at our institution were included in the study. The mean Expanded Prostate Cancer Index Composite bowel summary score at baseline was 90.1±11.0 compared with 71.5±22.8 (p=0.000), 70.1±20.7, 87.1±13.8 (p=0.01), and 90.7±9.2 (p=0.70) at 2 weeks and 1, 3, and 6 months postoperatively, respectively.
In men undergoing PB as monotherapy with (131)Cs, bowel symptoms returned to baseline by 3 months after the procedure. For patients undergoing PB with (131)Cs as part of combination therapy, bowel symptoms return to their post-external beam radiotherapy, pre-PB baseline by 3 months after the procedure.
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Details
- Title
- Acute bowel morbidity after prostate brachytherapy with cesium-131
- Creators
- Bruce L Jacobs - University of PittsburghErin P Gibbons - University of PittsburghRyan P Smith - University of PittsburghSushil Beriwal - University of PittsburghRonald M Benoit
- Publication Details
- Brachytherapy, v 10(1), pp 51-56
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000287003000011
- Scopus ID
- 2-s2.0-78651418246
- Other Identifier
- 991021897285704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging