Journal article
Acute zonal occult outer retinopathy: A case report
Optometry (Saint Louis, Mo.), v 81(1), pp 22-27
2010
PMID: 20004874
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Acute zonal occult outer retinopathy (AZOOR) is a disorder of unknown etiology with a predilection for young women. AZOOR is characterized by an acute loss of one or more zones of outer retinal function with a corresponding loss of visual field in one or both eyes. Patients present with photopsia, variable funduscopic changes, and abnormal electroretinogram (ERG) findings. There are no proven treatments. Diagnosed cases have a reasonable prognosis because central vision is often spared.
A 24-year-old white woman presented with acute photopsia with clouded temporal vision in the right eye (O.D.). Initial evaluation found a slightly swollen nerve fiber layer with no other outstanding lesions O.D. Over a 7-week follow-up period, there was significant progression into the deep chorioretinal tissues O.D. with an anterior chamber response. At 3 months, an afferent pupillary defect (APD) developed with significant retinal pigment epithelium (RPE) changes. After extensive testing, the consulting retinal specialist identified AZOOR as the etiology. At 21 and 31 months, the process remained in remission. Although primary symptoms subsided, the dense inferior-temporal field defect remained O.D.
AZOOR is a rare condition with subtle and often vague signs and symptoms making diagnosis difficult. The course of AZOOR, its clinical presentations, hypothesis of etiology, differential diagnosis, workup, management, and prognosis are reviewed.
Metrics
Details
- Title
- Acute zonal occult outer retinopathy: A case report
- Creators
- Josephine O. Ibironke - Johns Hopkins MedicineAndrew S. Gurwood - Drexel University Elkins Park Campus
- Publication Details
- Optometry (Saint Louis, Mo.), v 81(1), pp 22-27
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000293363700006
- Scopus ID
- 2-s2.0-71249136501
- Other Identifier
- 991022019499104721
UN Sustainable Development Goals (SDGs)
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology