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Adenocarcinoma of the lung presenting as thrombotic thrombocytopenic purpura
Journal article   Open access   Peer reviewed

Adenocarcinoma of the lung presenting as thrombotic thrombocytopenic purpura

Ahmed Dirweesh, Waqas Siddiqui, Muhammad Khan, Praneet Iyer, Marc Seelagy and Mahrukh Khan
Respiratory medicine case reports, v 21(C)
2017
DOI: https://doi.org/10.1016/j.rmcr.2017.04.004
PMID: 28417064
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1016/j.rmcr.2017.04.004View
Published, Version of Record (VoR)CC BY-NC-ND V4.0,  Open

Abstract

Adenocarcinoma Lung cancer Thrombotic microangiopathy Thrombotic thrombocytopenic purpura
Acquired thrombotic thrombocytopenic purpura (TTP) usually presents as severe microangiopathic hemolytic anemia (MAHA) and thrombocytopenia in a previously healthy individual. It occurs in approximately three in one million adults and 1 in 10 million children annually. The incidence is increased in females and blacks. Diagnosing TTP and initiating therapy with plasma exchange is a must to avoid preventable complications. Acquired thromotic microangiopathy has been linked to collagen vascular diseases, use of certain medications, organ transplants, infections, pregnancy and cancer. We report a rare case of a 56-year-old African American male diagnosed with TTP who found to have an asymptomatic adenocarcinoma of the lung. Prompt cancer management resulted in completed remission of the thrombotic microangiopathy.

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5 citations in Web of Science
6 citations in Scopus

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UN Sustainable Development Goals (SDGs)

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#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Respiratory System
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