Adenyl cyclase activity in the pineal gland of rats was determined by measuring the rate of formation of radioactive cyclic 3[image],5[image]-adenosine monophosphate from Cl4-labeled adenosine tri-phosphate. Norepinephrine added in vitro to pineal homogenates enhanced this activity, while denervation of the pineal gland by superior cervical ganglionectomy did not significantly reduce it. The enzyme in these denervated glands was more responsive to the stimulatory effects of norepinephrine.
Journal article
Adenyl Cyclase Activity in Rat Pineal Gland: Effects of Chronic Denervation and Norepinephrine
Science (American Association for the Advancement of Science), v 156(3783), pp 1750-1752
30 Jun 1967
PMID: 4305967
Abstract
Metrics
Details
- Title
- Adenyl Cyclase Activity in Rat Pineal Gland: Effects of Chronic Denervation and Norepinephrine
- Creators
- Benjamin Weiss - Columbia UniversityErminio Costa - Columbia University
- Publication Details
- Science (American Association for the Advancement of Science), v 156(3783), pp 1750-1752
- Publisher
- American Association for the Advancement of Science (AAAS); WASHINGTON
- Number of pages
- 1
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pharmacology and Physiology
- Web of Science ID
- WOS:A19679532000030
- Scopus ID
- 2-s2.0-0014221409
- Other Identifier
- 991020836335404721