Journal article
Adrenal Perivascular Epithelioid Cell Tumor A Case Report With Discussion of Differential Diagnoses
Archives of pathology & laboratory medicine (1976), v 135(4), pp 499-502
01 Apr 2011
PMID: 21466369
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A 50-year-old man presented with nausea and abdominal bloating sensation of a few months' duration and was found to have a large adrenal mass that was resected after computed tomography scan evaluation. The histopathologic examination showed epithelioid and spindle cells having clear to granular eosinophilic cytoplasm, and small, central, round to oval nuclei with small nucleoli. The tumor cells demonstrated reactivity for smooth muscle actin, HMB-45, Melan-A, and vimentin, with focal positivity for desmin and S100 protein and negative staining for inhibin, synaptophysin, and chromogranin. A diagnosis of perivascular epithelioid cell tumor was made. Perivascular epithelioid cell tumors can arise in a variety of locations, including omentum/mesentery, female genital tract, pelvic soft tissues, skin, and falciform ligament, but an adrenal primary tumor has not been previously reported, to the best of our knowledge. The differential diagnosis is broad and site-dependant and in our case includes several neoplasms with clear cells that can involve the adrenal gland, including a primary adrenocortical neoplasm. A review of the related literature and discussion of the differential diagnoses are presented. (Arch Pathol Lab Med. 2011;135:499-502)
Metrics
Details
- Title
- Adrenal Perivascular Epithelioid Cell Tumor A Case Report With Discussion of Differential Diagnoses
- Creators
- Alireza Zarineh - Drexel Univ, Coll Med, Allegheny Gen Hosp, Dept Pathol & Lab Med, Pittsburgh, PA 15212 USAJan F. Silverman
- Publication Details
- Archives of pathology & laboratory medicine (1976), v 135(4), pp 499-502
- Publisher
- Coll Amer Pathologists
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pathology (and Laboratory Medicine)
- Web of Science ID
- WOS:000289217200020
- Scopus ID
- 2-s2.0-79955089689
- Other Identifier
- 991019168406904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Medical Laboratory Technology
- Medicine, Research & Experimental
- Pathology