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Advanced Cell and Tissue Biomanufacturing
Journal article

Advanced Cell and Tissue Biomanufacturing

Kaiming Ye, David L Kaplan, Gang Bao, Christopher Bettinger, Gabor Forgacs, Cheng Dong, Ali Khademhosseini, Yonggang Ke, Kam Leong, Athanassios Sambanis, …
ACS biomaterials science & engineering, v 4(7), pp 2292-2307
09 Jul 2018
PMID: 33435095

Abstract

systems biology tissue biofabrication 3D bioprinting biosystem integration cell advanced manufacturing
This position paper assesses state-of-the-art advanced biomanufacturing and identifies paths forward to advance this emerging field in biotechnology and biomedical engineering, including new research opportunities and translational and corporate activities. The vision for the field is to see advanced biomanufacturing emerge as a discipline in academic and industrial communities as well as a technological opportunity to spur research and industry growth. To navigate this vision, the paths to move forward and to identify major barriers were a focal point of discussions at a National Science Foundation-sponsored workshop focused on the topic. Some of the major needs include but are not limited to the integration of specific scientific and engineering disciplines and guidance from regulatory agencies, infrastructure requirements, and strategies for reliable systems integration. Some of the recommendations, major targets, and opportunities were also outlined, including some “grand challenges” to spur interest and progress in the field based on the participants at the workshop. Many of these recommendations have been expanded, materialized, and adopted by the field. For instance, the formation of an initial collaboration network in the community was established. This report provides suggestions for the opportunities and challenges to help move the field of advanced biomanufacturing forward. The field is in the early stages of effecting science and technology in biomanufacturing with a bright and important future impact evident based on the rapid scientific advances in recent years and industry progress.

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#9 Industry, Innovation and Infrastructure

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Materials Science, Biomaterials
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