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Advances in Non-Small Cell Lung Cancer: Current Insights and Future Directions
Journal article   Open access   Peer reviewed

Advances in Non-Small Cell Lung Cancer: Current Insights and Future Directions

Pankaj Garg, Sulabh Singhal, Prakash Kulkarni, David Horne, Jyoti Malhotra, Ravi Salgia and Sharad S Singhal
Journal of clinical medicine, v 13(14), 4189
18 Jul 2024
PMID: 39064229
url
https://doi.org/10.3390/jcm13144189View
Published, Version of Record (VoR)CC BY V4.0 Open

Abstract

lung cancer diagnosis targeted therapies genetic profiling therapeutic resistance CAR-T cell therapy non-small cell lung cancer (NSCLC)
The leading cause of cancer deaths worldwide is attributed to non-small cell lung cancer (NSCLC), necessitating a continual focus on improving the diagnosis and treatment of this disease. In this review, the latest breakthroughs and emerging trends in managing NSCLC are highlighted. Major advancements in diagnostic methods, including better imaging technologies and the utilization of molecular biomarkers, are discussed. These advancements have greatly enhanced early detection and personalized treatment plans. Significant improvements in patient outcomes have been achieved by new targeted therapies and immunotherapies, providing new hope for individuals with advanced NSCLC. This review discusses the persistent challenges in accessing advanced treatments and their associated costs despite recent progress. Promising research into new therapies, such as CAR-T cell therapy and oncolytic viruses, which could further revolutionize NSCLC treatment, is also highlighted. This review aims to inform and inspire continued efforts to improve outcomes for NSCLC patients globally, by offering a comprehensive overview of the current state of NSCLC treatment and future possibilities.

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14 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Oncology
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