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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Air Pollution, Cardiovascular Outcomes, and Social Disadvantage The Multi-ethnic Study of Atherosclerosis
Epidemiology (Cambridge, Mass.), v 27(1)
01 Jan 2016
PMID: 26618771
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background: Social factors may enhance health effects of air pollution, yet empirical support is inconsistent. The interaction of social and environmental factors may only be evident with long-term exposures and outcomes that reflect long-term disease development.
Methods: We used cardiac magnetic resonance imaging data from the Multi-Ethnic Study of Atherosclerosis to assess left-ventricular mass index (LVMI) and left-ventricular ejection fraction (LVEF). We assigned residential concentrations of fine particulate matter (PM2.5), oxides of nitrogen, and nitrogen dioxide in the year 2000 to each participant in 2000 using prediction models. We examined modifying roles of four measures of adversity: race/ethnicity, racial/ethnic residential segregation, and socioeconomic status and psychosocial adversity as composite indices on the association between air pollution and LVMI or LVEF.
Results: Compared with whites, blacks showed a stronger adjusted association between air pollution and LVMI. For example, for each 5 mu g/m(3) greater PM2.5 level, whites showed a 1.0 g/m(2) greater LVMI (95% confidence interval = -1.3, 3.1), while blacks showed an additional 4.0 g/m(2) greater LVMI (95% confidence interval = 0.3, 8.2). Results were similar for oxides of nitrogen and nitrogen dioxide with regard to black race and LVMI. However, we found no evidence of a modifying role of other social factors or ethnic groups. Furthermore, we found no evidence of a modifying role for any social factors or racial/ethnic groups on the association between air pollution and LVEF.
Conclusions: Our results suggest that racial group membership may modify the association between air pollution and cardiovascular disease.
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Details
- Title
- Air Pollution, Cardiovascular Outcomes, and Social Disadvantage The Multi-ethnic Study of Atherosclerosis
- Creators
- Margaret T. Hicken - Univ Michigan, Ann Arbor, MI 48109 USASara D. Adar - University of WashingtonAnjum Hajat - University of WashingtonKiarri N. Kershaw - Northwestern UniversityD. Phuong Do - University of Wisconsin–MilwaukeeR. Graham Barr - Columbia UniversityJoel D. Kaufman - University of WashingtonAna V. Diez Roux - Drexel University
- Publication Details
- Epidemiology (Cambridge, Mass.), v 27(1)
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 9
- Grant note
- P2CHD041028 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) R01HL071759 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) N01HC095159 / DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) P60 MD002249 / Michigan Center for Integrative Approaches to Health Disparities - National Institute on Minority Health and Health Disparities K99ES023498 / NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) N01-HC-95159; N01-HC-95160; N01-HC-95161; N01-HC-95162; N01-HC-95163; N01-HC-95164; N01-HC-95165; N01-HC-95166; N01-HC-95167; N01-HC-95168; N01-HC-95169; R01-HL-071759 / National Heart, Lung, and Blood Institute (NHLBI); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) P60MD002249 / National Institute on Minority Health and Health Disparities; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Minority Health & Health Disparities (NIMHD) RD83169701 / US Environmental Protection Agency (EPA); United States Environmental Protection Agency
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000366318100008
- Scopus ID
- 2-s2.0-84949603915
- Other Identifier
- 991019168159204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health