Journal article
Air Pollution and Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis
Progress in cardiovascular diseases, v 53(5), pp 353-360
2011
PMID: 21414470
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Research to date demonstrates a relationship between exposure to ambient air pollutants and cardiovascular disease (CVD). Many studies have shown associations between short-term exposures to elevated levels of air pollutants and CVD events, and several cohort studies suggest effects of long-term exposure on cardiovascular mortality, coronary heart disease events, and stroke. The biologic mechanisms underlying this long-term exposure relationship are not entirely clear but are hypothesized to include systemic inflammation, autonomic nervous system imbalance, changes in vascular compliance, altered cardiac structure, and development of atherosclerosis. The Multi-Ethnic Study of Atherosclerosis provides an especially well-characterized population in which to investigate the relationship between air pollution and CVD and to explore these biologic pathways. This article reviews findings reported to date within this cohort and summarizes the aims and anticipated contributions of a major ancillary study, the Multi-Ethnic Study of Atherosclerosis and Air Pollution.
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Details
- Title
- Air Pollution and Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis
- Creators
- Edward A Gill - Department of Medicine, University of Washington, Seattle, WA 98105Cynthia L Curl - Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98105Sara D Adar - Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109Ryan W Allen - Department of Health Sciences, Simon Fraser University, Burnaby, BC V5Z 1M9, CanadaAmy H Auchincloss - Department of Epidemiology and Biostatistics, Drexel University, Philadelphia, PA 19102Marie S O'Neill - Department of Epidemiology and Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109Sung Kyun Park - Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109Victor C Van Hee - Department of Medicine, University of Washington, Seattle, WA 98105Ana V Diez Roux - Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109Joel D Kaufman - Department of Medicine, University of Washington, Seattle, WA 98105
- Publication Details
- Progress in cardiovascular diseases, v 53(5), pp 353-360
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000288922000004
- Scopus ID
- 2-s2.0-79952611540
- Other Identifier
- 991014877897604721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems