Files and links (1)
Published, Version of Record (VoR)Open Access via Drexel Libraries Read and Publish Program 2024CC BY V4.0, Open
Journal article - Review
Air Pollution and Temperature in Seizures and Epilepsy: A Scoping Review of Epidemiological Studies
Current environmental health reports, v 12(1), 1
10 Dec 2024
PMID: 39656387
Featured in Collection : Research Supported by Drexel Libraries' OA Programs
Abstract
Purpose of the Review
Seizures and epilepsy can be debilitating neurological conditions and have few known causes. Emerging evidence has highlighted the potential contribution of environmental exposures to the etiology of these conditions, possibly manifesting via neuroinflammation and increased oxidative stress in the brain. We conducted a scoping review of epidemiological literature linking air pollution and temperature exposures with incidence and acute aggravation of seizures and epilepsy. We systematically searched PubMed, Embase, Web of Science, and APA PsycINFO databases for peer-reviewed journal articles published in English from inception to February 7, 2024.
Recent Findings
We identified a total of 34 studies: 16 examined air pollution exposure, 12 ambient temperature, and six examined both air pollution and ambient temperature. Most studies were conducted in Asia (China, Taiwan, South Korea, and Japan). Nearly all studies retrospectively derived acute (daily average), ambient, and postnatal exposure estimates from ground monitoring systems and ascertained epilepsy cases or seizure events through record linkage with medical records, health registry systems, or insurance claims data. Commonly assessed exposures were particulate matter (PM2.5, PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO), ozone (O3), and daily mean ambient temperature. Overall, the main findings across studies lacked consistency, with mixed results reported for the associations of air pollutants and temperature metrics with both seizure incidence and acute aggravations of epilepsy.
Summary
An increasing number of studies have explored the relation of air pollution and temperature exposure with seizures and epilepsy. Research addressing the limitations of existing evidence is needed to arrive at more definitive causal conclusions.
Metrics
Details
- Title
- Air Pollution and Temperature in Seizures and Epilepsy: A Scoping Review of Epidemiological Studies
- Creators
- Rachit Sharma (Corresponding Author) - Drexel University, Environmental and Occupational HealthLeah Hope Schinasi - Drexel University, Urban Health CollaborativeBrian K Lee - Drexel University, Epidemiology and BiostatisticsJennifer Weuve - Boston UniversityMarc G Weisskopf - Harvard UniversityPerry E. Sheffield - Icahn School of Medicine at Mount SinaiJane E. Clougherty - Drexel University, Urban Health Collaborative
- Publication Details
- Current environmental health reports, v 12(1), 1
- Publisher
- Springer Nature
- Number of pages
- 15
- Grant note
- U.S. Environmental Protection Agency - Grant number R840472 National Institutes of Health - Grant number 1R01ES030717 National Heart, Lung, and Blood Institute - Grant number R01 HL164726-01A1
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics; Environmental and Occupational Health
- Web of Science ID
- WOS:001374150800001
- Scopus ID
- 2-s2.0-85211333452
- Other Identifier
- 991021969800304721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health