Journal article
Alcohol sipping patterns, personality, and psychopathology in Children: Moderating effects of dorsal anterior cingulate cortex (dACC) activation
Alcohol, clinical & experimental research, v 48(8), pp 1492-1506
Aug 2024
PMID: 38890123
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
BackgroundAlcohol, the most consumed drug in the United States, is associated with various psychological disorders and abnormal personality traits. Despite extensive research on adolescent alcohol consumption, the impact of early alcohol sipping patterns on changes in personality and mental health over time remains unclear. There is also limited information on the latent trajectory of early alcohol sipping, beginning as young as 9-10 years old. The dorsal anterior cingulate cortex (dACC) is crucial for cognitive control and response inhibition. However, the role of the dACC remains unclear in the relationship between early alcohol sipping and mental health outcomes and personality traits over time.MethodsUtilizing the large data from the Adolescent Brain Cognitive Development study (N = 11,686, 52% males, 52% white, mean [SD] age 119 [7.5] months, 9807 unique families, 22 sites), we aim to comprehensively examine the longitudinal impact of early alcohol sipping patterns on psychopathological measures and personality traits in adolescents, filling crucial gaps in the literature.ResultsWe identified three latent alcohol sipping groups, each demonstrating distinct personality traits and depression score trajectories. Bilateral dACC activation during the stop-signal task moderated the effect of early alcohol sipping on personality and depression over time. Additionally, bidirectional effects were observed between alcohol sipping and personality traits.ConclusionsThis study provides insights into the impact of early alcohol consumption on adolescent development. The key finding of our analysis is that poor response inhibition at baseline, along with increased alcohol sipping behaviors may accelerate the changes in personality traits and depression scores over time as individuals transition from childhood into adolescence.
Utilizing data from the Adolescent Brain Cognitive Development (ABCD) study, we investigate the latent trajectory of early alcohol sipping and its impact on personality and mental health over time. We identify three latent alcohol sipping groups, each with distinct personality traits and depression score trajectories. Key findings reveal that increased alcohol sipping behaviors and poor response inhibition at baseline may accelerate changes in personality traits and depression scores over time, with bilateral dorsal anterior cingulate cortex (dACC) activation moderating these effects.image
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Details
- Title
- Alcohol sipping patterns, personality, and psychopathology in Children: Moderating effects of dorsal anterior cingulate cortex (dACC) activation
- Creators
- Ana Ferariu - Drexel UniversityHansoo Chang - Drexel UniversityAlexei Taylor - Drexel UniversityFengqing Zhang - Drexel University
- Publication Details
- Alcohol, clinical & experimental research, v 48(8), pp 1492-1506
- Publisher
- Wiley
- Number of pages
- 15
- Grant note
- U01DA041048; U01DA050989; U01DA051016; U01DA041022; U01DA051018; U01DA051037; U01DA050987; U01DA041174; U01DA041106; U01DA041117; U01DA041028; U01DA041134; U01DA050988; U01DA051039; U01DA041156; U01DA041025; U01DA041120; U01DA051038; U01DA041148; U01DA041093; U01DA041089; U24DA041123; U24DA041147 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:001249087800001
- Scopus ID
- 2-s2.0-85196301218
- Other Identifier
- 991021891315504721
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- Web of Science research areas
- Substance Abuse