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Altered Electron Flow in Continuous Cultures of Clostridium acetobutylicum Induced by Viologen Dyes
Journal article   Open access   Peer reviewed

Altered Electron Flow in Continuous Cultures of Clostridium acetobutylicum Induced by Viologen Dyes

Govind Rao and R. Mutharasan
Applied and environmental microbiology, v 53(6), pp 1232-1235
01 Jun 1987
PMID: 16347357
url
https://doi.org/10.1128/aem.53.6.1232-1235.1987View
Published, Version of Record (VoR)Open Access (License Unspecified) Open

Abstract

Physiology and Biotechnology
The physiological response of Clostridium acetobutylicum to methyl and benzyl viologen was investigated. Viologen dyes at low concentrations (at levels of parts per million [micrograms per milliliter]) caused significant metabolic shifts. Altered electron flow appeared to direct carbon flow from acid to alcohol production accompanied by decreased hydrogen evolution. Reducing equivalents normally released as free hydrogen were directed toward formation of NADH which, in turn, resulted in increased alcohol production. In addition, it was shown that solvent production can take place at pH 6.3. Contrary to previous reports, butanol production appears to be independent of high levels of acetate-butyrate and glucose.

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Web of Science research areas
Biotechnology & Applied Microbiology
Microbiology
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