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Alternative modified infant-feeding practices to prevent postnatal transmission of human immunodeficiency virus type 1 through breast milk: past, present, and future
Journal article   Peer reviewed

Alternative modified infant-feeding practices to prevent postnatal transmission of human immunodeficiency virus type 1 through breast milk: past, present, and future

Sandra Urdaneta Hartmann, Cheston M Berlin and Mary K Howett
Journal of human lactation, v 22(1)
Feb 2006
PMID: 16467289

Abstract

HIV-1 HIV Infections - prevention & control Humans Risk Factors Infant Milk, Human - virology Forecasting Preventive Health Services Adult Female HIV Infections - transmission Developing Countries Infectious Disease Transmission, Vertical - prevention & control Infant, Newborn
Preventing mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) through breastfeeding is important to reduce the number of infected children. Research on making breastfeeding safer is a high priority. The authors reviewed the attempts to develop alternative methods, other than antiretroviral (ARV) therapy of mothers and/or babies, to decontaminate breast milk of infectious HIV-1 (free and associated with lymphocytes). They also review how these methods affect milk constituents, as well as their current and prospective status. A PubMed search for English publications on methods to prevent MTCT through breast milk was completed. Methods that have been tested, other than systemicuse or ARV or immunoprophylaxis, to reduce or prevent MTCT of HIV-1 through breast milk were broadly classified into 5 groups: (1) modified feeding practices, (2) heat treatment of milk, (3) lipolysis, (4) antimicrobial treatment of the breastfeeding mother, and (5) microbicidal treatment of infected milk. Their advantages and disadvantages are discussed, as well as future directions in the prevention of MTCT through breastfeeding.

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Collaboration types
Domestic collaboration
Web of Science research areas
Nursing
Obstetrics & Gynecology
Pediatrics
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