Journal article
Alzheimer’s Disease in 22 Twin Pairs – 13-Year Follow-Up: Hormonal, Infectious and Traumatic Factors
Dementia and geriatric cognitive disorders, v 10(2), pp 148-151
Apr 1999
PMID: 10026389
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We obtained follow-up data on 22 sets of twins where at least one twin had Alzheimer’s disease (AD). The concordance rate for monozygotic twins (n = 17 pairs) was 59%, whereas that for dizygotic twins was 40%. In our series 8 monozygotic twins had hysterectomies; all had AD. The twins with hysterectomies also had a tendency to develop AD at an earlier age than their co-twin. Five twins with serious systemic infection developed AD, and they tended to have earlier onset than their corresponding twin. We found no strong evidence that head injury predisposed to AD.
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Details
- Title
- Alzheimer’s Disease in 22 Twin Pairs – 13-Year Follow-Up: Hormonal, Infectious and Traumatic Factors
- Creators
- Linda E Nee - National Institute of Neurological Disorders and StrokeCarol F Lippa
- Publication Details
- Dementia and geriatric cognitive disorders, v 10(2), pp 148-151
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000078947100014
- Scopus ID
- 2-s2.0-0033021455
- Other Identifier
- 991019312381804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Geriatrics & Gerontology
- Psychiatry