Journal article
Ambient ozone exposure and children's acute asthma in New York City: a case-crossover analysis
Environmental health, v 14(1), pp 25-25
18 Mar 2015
PMID: 25889205
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Childhood asthma morbidity has been associated with ambient ozone in case-crossover studies. Varying effects of ozone by child age and sex, however, have been less explored.
This study evaluates associations between ozone exposure and asthma emergency department visits and hospitalizations among boys and girls aged 5-17 years in New York City for the 2005-2011 warm season period. Time-stratified case-crossover analysis was conducted and, for comparison, time-series analysis controlling for season, day-of-week, same-day and delayed effects of temperature and relative humidity were also performed.
We found associations between ambient ozone levels and childhood asthma emergency department visits and hospitalizations in New York City, although the relationships varied among boys and girls and by age group. For an increase of interquartile range (0.013 ppm) in ozone, there was a 2.9-8.4% increased risk for boys and 5.4-6.5% for girls in asthma emergency department visits; and 8.2% increased risk for girls in hospitalizations. Among girls, we observed stronger associations among older children (10-13 and 14-17 year age groups). We did not observe significant modification by age for boys. Boys exhibited a more prompt response (lag day 1) to ozone than did girls (lag day 3), but significant associations for girls were retained longer, through lag day 6.
Our study indicates significant variance in associations between short-term ozone concentrations and asthma events by child sex and age. Differences in ozone response for boys and girls, before and after puberty, may point towards both social (gendered) and biological (sex-linked) sources of effect modification.
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Details
- Title
- Ambient ozone exposure and children's acute asthma in New York City: a case-crossover analysis
- Creators
- Perry Elizabeth Sheffield - Icahn School of Medicine at Mount SinaiJiang Zhou - University of PittsburghJessie Loving Carr Shmool - University of PittsburghJane Ellen Clougherty - University of Pittsburgh
- Publication Details
- Environmental health, v 14(1), pp 25-25
- Publisher
- Springer BMC
- Grant note
- K23 ES024127 / NIEHS NIH HHS P30 ES023515 / NIEHS NIH HHS L40 ES017745 / NIEHS NIH HHS K23ES024127 / NIEHS NIH HHS R21ES021429 / NIEHS NIH HHS R21 ES021429 / NIEHS NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Dana and David Dornsife School of Public Health; Drexel University; Environmental and Occupational Health
- Web of Science ID
- WOS:000352102100001
- Scopus ID
- 2-s2.0-84925433287
- Other Identifier
- 991020099116504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health