Journal article
American Brachytherapy Society recurrent carcinoma of the endometrium task force patterns of care and review of the literature
Brachytherapy, v 16(6), pp 1129-1143
Nov 2017
PMID: 28888417
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The purpose of this American Brachytherapy Society task force is to present a literature review and patterns of care by a panel of experts for the management of vaginal recurrence of endometrial cancer.
In 2016, the American Brachytherapy Society Board selected a panel of experts in gynecologic brachytherapy to update our current state of knowledge for managing vaginal recurrence of endometrial cancer. Practice patterns were evaluated via an online survey and clinical updates occurred through a combination of literature review and clinical experience and/or expertise.
There are various retrospective series of patients treated with radiation for vaginal recurrence of endometrial cancer, which include a varied group of patients, multiple treatment techniques, and a range of total doses and demonstrate a wide scope of local control and overall survival outcomes. In the era of image-guided brachytherapy, high local control rates with low significant late-term morbidities can be achieved. Lower rates of local control and higher late-term toxicity are reported in the retreatment setting. In patients with no previous history of radiation treatment, external beam radiation therapy followed by brachytherapy boost should be used. There are varying practices with regard to the definition and appropriate doses of both the high-risk clinical target volume and the intermediate-risk clinical target volume in the setting of vaginal recurrence of endometrial cancer. There are limited data to provide appropriate dose constraints for some organs at risk with the majority of guidance taken from the definitive cervical cancer literature.
A summary of literature and expert practice patterns for patient selection, dose recommendations, and constraints are provided as guidance for practitioners.
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Details
- Title
- American Brachytherapy Society recurrent carcinoma of the endometrium task force patterns of care and review of the literature
- Creators
- Mitchell Kamrava - Cedars-Sinai Medical CenterSushil Beriwal - University of PittsburghBeth Erickson - Medical College of WisconsinDavid Gaffney - University of UtahAnuja Jhingran - The University of Texas MD Anderson Cancer CenterAnn Klopp - The University of Texas MD Anderson Cancer CenterSang June Park - Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CAAkila Viswanathan - Johns Hopkins UniversityCatheryn Yashar - University of California, San DiegoLilie Lin - The University of Texas MD Anderson Cancer Center
- Publication Details
- Brachytherapy, v 16(6), pp 1129-1143
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000417012400008
- Scopus ID
- 2-s2.0-85028747582
- Other Identifier
- 991021897271904721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging