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An Assessment of the Usefulness of the Duke Criteria for Diagnosing Active Infective Endocarditis
Journal article   Open access   Peer reviewed

An Assessment of the Usefulness of the Duke Criteria for Diagnosing Active Infective Endocarditis

Mikkael A. Sekeres, Elias Abrutyn, Jesse A. Berlin, Donald Kaye, Judith L. Kinman, Oksana M. Korzeniowski, Matthew E. Levison, Roy S. Feldman and Brian L. Strom
Clinical infectious diseases, v 24(6), pp 1185-1190
Jun 1997
PMID: 9195080
url
https://doi.org/10.1086/513657View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

We evaluated the usefulness of the Duke criteria for diagnosing cases of active infective endocarditis (IE). Patients were identified prospectively over a 3-year period at 54 hospitals in the Philadelphia metropolitan area. Three of us independently reviewed abstracted hospital records and classified 410 patients as definite, probable, or possible cases of IE or as probable noncases. We then applied the Duke criteria to this sample to assess the degree of agreement between our diagnoses and the diagnoses based on these new criteria. Agreement was good to excellent, ranging from 72% to 90%, depending on the case definition used. The sensitivity of the Duke criteria was also good to excellent, varying from 71% to 99%, again depending on case definition used. Specificity was lower (0–89%). We conclude that use of the Duke criteria will result in little underdiagnosis of IE but that it may result in overdiagnosis of IE; therefore, these criteria should be applied prospectively to determine their clinical usefulness.

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Collaboration types
Domestic collaboration
Web of Science research areas
Immunology
Infectious Diseases
Microbiology
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