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An Exploration of Pre-exposure Prophylaxis (PrEP) Initiation Among Women Who Inject Drugs
Journal article   Open access   Peer reviewed

An Exploration of Pre-exposure Prophylaxis (PrEP) Initiation Among Women Who Inject Drugs

Marisa Felsher, Eliza Ziegler, Laramie R Smith, Susan G Sherman, K Rivet Amico, Rachel Fox, Kayla Madden and Alexis M Roth
Archives of sexual behavior, v 49(6), pp 2205-2212
Aug 2020
PMID: 32274742
url
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773227View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Adult Female HIV Infections - prevention & control Humans Pre-Exposure Prophylaxis - methods Substance Abuse, Intravenous - therapy
Pre-exposure prophylaxis (PrEP) is an effective but understudied tool for preventing HIV among women who inject drugs (WWID). This article is the first to explore WWID's rationale for PrEP initiation (or refusal) in a real-world setting. Purposive sampling was used to recruit 25 WWID, participating in a PrEP demonstration project operating within a syringe services program, based on whether they initiated or declined PrEP care. Content analysis of qualitative interviews was used to explore decisions to initiate PrEP (or not). We found that WWID view HIV as severe, perceive themselves to be susceptible to HIV, and believe PrEP is beneficial for HIV prevention. For some, however, real and perceived barriers outweighed benefits, leading to decisions not to initiate PrEP. Barriers included HIV stigma, fear of side effects, and needing assurance that PrEP care will be available long-term. Despite viewing PrEP as an important HIV prevention tool, not all WWID who were offered PrEP initiated it. For these women, supports to buffer perceived barriers to initiation and access to post-exposure prophylaxis may be warranted. For women who initiate, it is possible that adherence will wane if perceived risk does not remain high. Research to understand PrEP persistence is needed.

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31 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Psychology, Clinical
Social Sciences, Interdisciplinary
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