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An Extremely Premature Neonate With Recurrent Hypoxic Respiratory Failure
Journal article   Peer reviewed

An Extremely Premature Neonate With Recurrent Hypoxic Respiratory Failure

Saritha Beauchamp, Vilmaris Quinones Cardona, Emily Souder and Swosti Joshi
Neoreviews (Elk Grove Village, Ill.), v 27(9), pp e581-e584
01 Sep 2026
PMID: 42674612
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Abstract

Hypoxia Infants
A 760-g male infant is born to a primigravida mother at an estimated 25 + 0 weeks of gestation via spontaneous vaginal delivery. The mother is not aware of pregnancy, and hence she does not seek prenatal care; maternal laboratories at the time of delivery are significant for untreated maternal chlamydia infection. The neonate’s Apgar scores are 0 and 6 at 1 and 5 minutes, respectively. Physical examination reveals an appropriate-for-gestational-age male neonate with mild respiratory distress. The neonate is admitted to the neonatal intensive care unit (NICU) for prematurity and respiratory distress on noninvasive respiratory support till day of life 6. On day 7 after birth, the respiratory status worsens, prompting intubation. A sepsis workup, including blood and urine cultures, is negative. Chlamydia Polymerase chain reaction (PCR) test with amplified DNA is negative. He continues to require invasive ventilation for the next 10 days.

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