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An In-line, High Sensitivity, Non-contact Sensor for the Detection of Initiation of Sticking
Journal article   Peer reviewed

An In-line, High Sensitivity, Non-contact Sensor for the Detection of Initiation of Sticking

James Thomas and Antonios Zavaliangos
Journal of pharmaceutical innovation, v 15(1), pp 66-72
2020

Abstract

Biochemical Engineering Biomedical and Life Sciences Biomedicine Biotechnology Industrial and Production Engineering Original Article Pharmacology/Toxicology
Purpose In this paper, the development and testing of a laser sensor to detect initiation of sticking are discussed. Method The basic working principle of the device involves a laser source aimed at the punch tip, and a photosensor measuring the intensity of the reflected beam. Results The initial results show that the laser sensor can detect the accumulation of material on a flat punch tip and has the potential to be used as a real-time monitoring device during tablet manufacturing operations. Conclusions This work demonstrated that the laser sensor can characterize initiation of sticking with high sensitivity without the need to interrupt the compaction process as typically done with other sticking characterization techniques.

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2 citations in Scopus

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Collaboration types
Industry collaboration
Domestic collaboration
Web of Science research areas
Pharmacology & Pharmacy
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