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An Update on the Current Role of High Resolution Anoscopy in Patients With Anal Dysplasia
Journal article   Open access   Peer reviewed

An Update on the Current Role of High Resolution Anoscopy in Patients With Anal Dysplasia

Anuragh Gudur, Deepak Shanmuganandamurthy, Zsofia Szep and Juan Lucas Poggio
Anticancer research, v 39(1), pp 17-23
01 Jan 2019
PMID: 30591436
url
https://doi.org/10.21873/anticanres.13075View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

Life Sciences & Biomedicine Oncology Science & Technology
The incidence of anal squamous cell carcinoma (ASCC) in the U.S. is increasing, particularly in immunocompromised patients. Preventative screening is used to monitor precancerous dysplasia known as anal intraepithelial neoplasia (AIN), which can progress to ASCC. High Resolution Anoscopy (HRA) is one screening procedure that uses a colposcope with acetic acid and Lugol's iodine solution to visualize the anal epithelium for AIN. HRA has offered potential in managing AIN, but as more evidence emerges it is unclear whether HRA provides definitive benefit. This narrative review updates readers on the efficacy of HRA in screening AIN, compares HRA to other techniques, compares the use of HRA in various high-risk populations, and offers practical information on the use of HRA. Keyword searches were conducted using MEDLINE, Web of Science, and Cochrane Library. Current literature is mixed regarding the utility of HRA. Further randomized controlled trials are needed to definitively assess the role of HRA.

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14 citations in Scopus

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#5 Gender Equality
#3 Good Health and Well-Being

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Web of Science research areas
Oncology
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