Journal article
An efficient hydration of nitriles with ruthenium-supported heterogeneous catalyst in water under moderate conditions
Journal of industrial and engineering chemistry (Seoul, Korea), v 99, pp 187-195
25 Jul 2021
Abstract
[Display omitted]
A facile eco-friendly heterogeneous catalytic system has been developed for amide synthesis that further utilized in pharmaceutical and organic chemistry. The Ru/MnO2 catalyst has shown outstanding and unprecedented activity for a wide range of aliphatic and benzylic nitriles in green solvent water at 60°C. The system has also exhibited a remarkable tolerance for selective hydration of heteroatom (e.g. nitrogen, oxygen and sulphur atoms) containing nitriles. Pharmaceutically important nicotinamides and pyrazinamide has been synthesized by hydration of the heteroatomic nitriles with appreciable yields and selectivities. Moreover, the Ru/MnO2 catalyst has employed water as a benign solvent, with more than 30,000TONs and reusability five times after isolation from the reaction mixture by centrifugation and easy workup that established a path for green environmental and technologically acceptable protocol.
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Details
- Title
- An efficient hydration of nitriles with ruthenium-supported heterogeneous catalyst in water under moderate conditions
- Creators
- Muhammad Asif Hussain - Department of Metallurgical and Materials Engineering, University of Engineering and Technology, Lahore 39161, PakistanEun Ju Choi - Department of Chemical Engineering, Kangwon National University, Samcheok, Gangwon-do 25913, Republic of KoreaAdnan Maqbool - Department of Metallurgical and Materials Engineering, University of Engineering and Technology, Lahore, 39161, PakistanMuhammad Atif - University of EducationHassan Zeb - University of the PunjabJaeGoo Yeo - Department of Chemical Engineering Kangwon National University Samcheok Gangwon‐do 25913 Republic of KoreaJung-A Yu - Department of Chemical Engineering Kangwon National University Samcheok Gangwon‐do 25913 Republic of KoreaYong-Hun Cho - Department of Chemical Engineering Kangwon National University Samcheok Gangwon‐do 25913 Republic of KoreaMoses Noh - Drexel UniversityJung Won Kim - Kangwon National University
- Publication Details
- Journal of industrial and engineering chemistry (Seoul, Korea), v 99, pp 187-195
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000655693700004
- Scopus ID
- 2-s2.0-85106105459
- Other Identifier
- 991019167725504721
InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Chemistry, Multidisciplinary
- Engineering, Chemical