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Journal article
An empirical examination of appetite hormones and cognitive and behavioral bulimic symptomatology
Eating and weight disorders, v 26(4), pp 1129-1137
May 2021
PMID: 32951131
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Existing literature has demonstrated that appetite hormones are frequently dysregulated in individuals with bulimic-spectrum eating disorders (BN-EDs). Although dysregulations in appetite hormones may maintain BN-EDs, very limited research has examined the association between dysregulated appetite hormones and cognitive and behavioral bulimic symptoms. We hypothesized that greater frequency of behavioral symptoms and severity of cognitive symptoms of BN-EDs would correlate with greater dysregulation in appetite hormones.
The association between ghrelin, cortisol, leptin, GLP-1, and amylin levels and eating pathology was examined in treatment-seeking adults with BN-EDs (N = 33). Participants completed bloodwork to assess fasting blood hormone levels and bulimic symptoms were measured by the Eating Disorder Examination. Pearson partial correlations were run to examine the association between hormone levels and eating pathology, controlling for BMI.
Contrary to hypotheses, none of the appetite hormones tested were significantly associated with frequency of behavioral ED symptoms (p range = 0.13-0.97, negligible to small effect sizes). Global eating pathology was positively associated with leptin (p = 0.03) and negatively associated with GLP-1 (p = 0.03) and amylin (p = 0.04), with medium effect sizes. Post hoc analyses indicated significantly stronger associations between appetite hormones and cognitive eating pathology than between appetite hormones and frequency of binge eating [GLP-1 (p = 0.02) and amylin (p = 0.02)] or compensatory behaviors [leptin (p = 0.03), GLP-1 (p = 0.02), and amylin (p = 0.04)].
In individuals with BN-EDs, appetite hormones may be more strongly associated with cognitive symptoms than behavioral symptoms.
Level V, cross-sectional descriptive study.
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Details
- Title
- An empirical examination of appetite hormones and cognitive and behavioral bulimic symptomatology
- Creators
- Emily K Presseller - Drexel UniversityKelsey E Clark - Drexel UniversityCaroline Fojtu - Drexel UniversityAdrienne S Juarascio - Drexel University
- Publication Details
- Eating and weight disorders, v 26(4), pp 1129-1137
- Publisher
- Springer Nature
- Grant note
- K23MH105680 / NIMH NIH HHS K23 MH105680 / NIMH NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology); Center for Weight, Eating and Lifestyle Science (WELL) [Historical]
- Web of Science ID
- WOS:000571366900003
- Scopus ID
- 2-s2.0-85091143883
- Other Identifier
- 991019168294704721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Psychiatry