Journal article
Analysis of TAP1 and TAP2 Polymorphism of Mother-Infant in Chinese Patients with Pre-Eclampsia
Cellular & molecular immunology, v 2(2), pp 141-144
01 Apr 2005
PMID: 16191421
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To analyze the polymorphism of TAP gene and the shared rates of alleles between mothers and their infants in Chinese patients with pre-eclampsia, TAP1 and TAP2 genotyping was performed by the amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) in 42 patients, 106 normal pregnant women, and their neonates. The allelic frequency of TAP and the alleles shared in maternal-fetus were compared and analyzed in the two groups. Our results showed that, with totally eight alleles of TAP1 and TAP2 examined in the samples, no significant difference was found in allelic frequencies between pre-eclampsia group and control group, as well as between mothers and their neonates. Similar finding was obtained in the comparison with shared alleles. In conclusion, our results do not support a role for the polymorphisms of TAP in the etiology of pre-eclampsia.
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Details
- Title
- Analysis of TAP1 and TAP2 Polymorphism of Mother-Infant in Chinese Patients with Pre-Eclampsia
- Creators
- Zhan Zhang - Zhengzhou UniversityLiting Jia - Zhengzhou UniversityLei Hou - Zhengzhou UniversityPing Xiong - College Station Medical CenterXiongwen Wu - College Station Medical CenterXuemei Wang - Zhengzhou UniversityYafei Huang - College Station Medical CenterHangjun Ke - College Station Medical CenterCaihong Chang - Zhengzhou UniversityShihong Cui - Zhengzhou UniversityFeili Gong - College Station Medical Center
- Publication Details
- Cellular & molecular immunology, v 2(2), pp 141-144
- Publisher
- Springer Nature
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology; College of Medicine; Drexel University
- Web of Science ID
- WOS:000208924900009
- Scopus ID
- 2-s2.0-32944466638
- Other Identifier
- 991020100182704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Immunology