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Journal article
Anatomical Location of the Vesical Branches of the Inferior Hypogastric Plexus in Human Cadavers
Diagnostics (Basel), v 14(8), 794
01 Apr 2024
PMID: 38667441
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We have demonstrated in canines that somatic nerve transfer to vesical branches of the inferior hypogastric plexus (IHP) can be used for bladder reinnervation after spinal root injury. Yet, the complex anatomy of the IHP hinders the clinical application of this repair strategy. Here, using human cadavers, we clarify the spatial relationships of the vesical branches of the IHP and nearby pelvic ganglia, with the ureteral orifice of the bladder. Forty-four pelvic regions were examined in 30 human cadavers. Gross post-mortem and intra-operative approaches (open anterior abdominal, manual laparoscopic, and robot-assisted) were used. Nerve branch distances and diameters were measured after thorough visual inspection and gentle dissection, so as to not distort tissue. The IHP had between 1 to 4 vesical branches (2.33 +/- 0.72, mean +/- SD) with average diameters of 0.51 +/- 0.06 mm. Vesical branches from the IHP arose from a grossly visible pelvic ganglion in 93% of cases (confirmed histologically). The pelvic ganglion was typically located 7.11 +/- 6.11 mm posterolateral to the ureteral orifice in 69% of specimens. With this in-depth characterization, vesical branches from the IHP can be safely located both posterolateral to the ureteral orifice and emanating from a more proximal ganglionic enlargement during surgical procedures.
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Details
- Title
- Anatomical Location of the Vesical Branches of the Inferior Hypogastric Plexus in Human Cadavers
- Creators
- Emily P. Day - Drexel University, College of MedicineBenjamin R. Johnston - Brigham and Women's HospitalStanley F. Bazarek - Brigham and Women's HospitalJustin M. Brown - Massachusetts General HospitalNucelio Lemos - University of TorontoEve I. Gibson - Temple UniversityHelaina N. Hurban - Temple UniversitySusan B. Fecho - Barton CollegeLewis Holt-Bright - Temple UniversityDaniel D. Eun - Temple UniversityMichel A. Pontari - Temple Univ, Lewis Katz Sch Med, Philadelphia, PA 19140 USAElise J. De - Massachusetts General HospitalFrancis J. McGovern - Massachusetts General HospitalMichael R. Ruggieri - Shriners Hospitals for Children - PhiladelphiaMary F. Barbe - Temple University
- Publication Details
- Diagnostics (Basel), v 14(8), 794
- Publisher
- Mdpi
- Number of pages
- 17
- Grant note
- National Institute of Neurological Disorders and Stroke; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:001210268900001
- Scopus ID
- 2-s2.0-85191364775
- Other Identifier
- 991022005884904721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Surgery