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Antidepressant Treatments in Children and Adolescents I. Affective Disorders
Journal article

Antidepressant Treatments in Children and Adolescents I. Affective Disorders

PAUL J. Ambrosini, MICHAEL D. Bianchi, HARRIS Rabinovich and JOSEPHINE Elia
Journal of the American Academy of Child and Adolescent Psychiatry, v 32(1)
1993
PMID: 8428861

Abstract

affective disorders antidepressants treatment efficacy
Part I of this review critically evaluates antidepressants' benefits for children and adolescents with affective disorders. The effectiveness of antidepressants is characterized with specific references regarding diagnostic methodology, measurement characteristics, response definitions, recovery rates, length of treatment, and plasma level monitoring. Antidepressants' efficacy for depressed youths is quite circumscribed, and their superiority to placebo remains unproved. Their intriguing lack of efficacy in affective disorders is discussed based on methodological issues and from a theoretical perspective. Clinical and research implications are presented.

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Web of Science research areas
Pediatrics
Psychiatry
Psychology, Developmental
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