Journal article
Antiviral potentials of medicinal plants
Virus research, v 131(2)
Feb 2008
PMID: 17981353
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Medicinal plants have been widely used to treat a variety of infectious and non-infectious ailments. According to one estimate, 25% of the commonly used medicines contain compounds isolated from plants. Several plants could offer a rich reserve for drug discovery of infectious diseases, particularly in an era when the latest separation techniques are available on one hand, and the human population is challenged by a number of emerging infectious diseases on the other hand. Among several other ailments, viral infections, particularly infections associated with human immunodeficiency virus type 1 (HIV-1) and 2 (HIV-2), and newly emerging infectious viruses have challenged mankind survival. Of importance, a variety of medicinal plants have shown promise to treat a number of viral infections, and some of them possess broad-spectrum antiviral activity. In the past, exploration into the antiviral activity of various promising medicinal plants was limited due to: (a) highly infectious nature of viruses and (b) lack of appropriate separation techniques for the identification of antiviral components from plants. Development of vector-based strategies, in which non-infectious molecular clone of a virus could be used for antiviral screening purposes, and advancement in separation technologies offers promise for medicinal plants usage in modern drug discovery. This article describes potential antiviral properties of medicinal plants against a diverse group of viruses, and suggests screening the potential of plants possessing broad-spectrum antiviral effects against emerging viral infections.
Metrics
Details
- Title
- Antiviral potentials of medicinal plants
- Creators
- Muhammad Mukhtar - University of Arid Agriculture Rawalpindi, Murree Road,Rawalpindi 46300, PakistanMohammad Arshad - The Islamia University of Bahawalpur, PakistanMahmood Ahmad - The Islamia University of Bahawalpur, PakistanRoger J Pomerantz - Tibotec Inc., Yardley, PA, USABrian Wigdahl - Department of Microbiology and Immunology, Institute for Molecular Medicine and Infectious Diseases, Drexel University College of Medicine, Philadelphia, PA 19102, USAZahida Parveen - Division of Infectious Diseases, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
- Publication Details
- Virus research, v 131(2)
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000253786200001
- Scopus ID
- 2-s2.0-38849181024
- Other Identifier
- 991014878143004721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Virology