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Applying a Bayesian spatiotemporal model to examine excess county-level cardiovascular disease death rates during the COVID-19 pandemic
Journal article   Open access   Peer reviewed

Applying a Bayesian spatiotemporal model to examine excess county-level cardiovascular disease death rates during the COVID-19 pandemic

Adam S. Vaughan, Harrison Quick, Kara B. Beck, Rebecca C. Woodruff, David Delara and Michele Casper
American journal of epidemiology, v 194(6), pp 1556-1565
01 Jun 2025
PMID: 39218426
url
https://doi.org/10.1093/aje/kwae330View
Published, Version of Record (VoR) Open

Abstract

Life Sciences & Biomedicine Public, Environmental & Occupational Health Science & Technology
Amid the COVID-19 pandemic, national cardiovascular disease (CVD) death rates increased, especially among younger adults. County-level variation has not been documented. Using county-level CVD deaths (ICD-10 codes: I00-I99) from the US National Vital Statistics System, we developed a Bayesian multivariate spatiotemporal model to estimate excess CVD death rates in 2020 based on trends from 2010 to 2019 for adults aged 35-64 and >= 65 years. Among adults aged 35-64 years, 64.7% of counties experienced significant excess CVD death rates. The median county-level CVD death rate in 2020 was 150 per 100 000 persons, which exceeded the predicted rate for 2020 (median excess death rate, 11 per 100 000; median excess rate ratio, 1.08). Among adults aged >= 65 years, 15.2% of counties experienced significant excess CVD death rates. The median county-level CVD death rate was 1546 per 100 000 in 2020, which exceeded the predicted rate in 2020 (median excess death rate, 48 per 100 000; median excess rate ratio, 1.03). Counties with significant excess death rates in 2020 were geographically dispersed. In 2020, disruptions of county-level CVD death rates were widespread, especially among younger adults, suggesting the continued importance of CVD prevention and treatment in younger adults in communities across the country.

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Public, Environmental & Occupational Health
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