Journal article
Are gender differences in schizophrenia reflected in brain event-related potentials?
Schizophrenia bulletin, v 16(2), pp 229-246
01 Jan 1990
PMID: 2374882
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Numerous studies have reported relationships between gender and cerebral event-related potentials (ERPs) recorded from the human scalp. Recent studies have suggested that the influences of gender on ERPs may differ in persons with schizophrenia compared to healthy controls. In a further evaluation of the influences of this critical subject variable on ERP characteristics in schizophrenia, ERPs of age- and gender-matched groups (n = 72 each) of unmedicated schizophrenic patients and healthy controls were compared. ERPs elicited by left and right median nerve stimulation, checkerboard pattern visual flash, and auditory clicks were recorded from 15 scalp leads. The results confirm previous findings showing that: (1) number of comparable gender effects present in the ERP records of these two large study groups and (2) specific Diagnosis x Gender interactions suggesting that schizophrenic illness may modify normal gender influences on ERP characteristics. These data illustrate the point that matching schizophrenic patients and healthy control populations for gender is essential but not sufficient. Even in carefully matched groups, gender confounding can persist as a source of error variance because the influence can vary for different diagnostic groups. (PsycInfo Database Record (c) 2020 APA, all rights reserved) (Source: journal abstract)
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Details
- Title
- Are gender differences in schizophrenia reflected in brain event-related potentials?
- Creators
- Richard C Josiassen - Drexel UniversityRichard A Roemer - Temple UniversityMichele M Johnson - Unit on Experimental Psychopathology, Medical College of Pennsylania/EPPIPhiladelphia, PACharles Shagass - Temple University
- Publication Details
- Schizophrenia bulletin, v 16(2), pp 229-246
- Publisher
- National Institute of Mental Health
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry
- Web of Science ID
- WOS:A1990DJ99400008
- Scopus ID
- 2-s2.0-0025356587
- Other Identifier
- 991019184044604721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychiatry