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Argon laser angioplasty with a laser probe
Journal article   Open access   Peer reviewed

Argon laser angioplasty with a laser probe

Yeng Yang, Makoto Hashizume, David Arbutina, Leonard F. Milewski, Joseph DuPree, Teruo Matsumoto and Yonghong F Yang
Journal of vascular surgery, v 6(1), pp 60-65
1987
PMID: 3599282
url
https://doi.org/10.1067/mva.1987.avs0060060View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

A preliminary basic study of argon laser angioplasty with the use of a specially designed probe is presented. Arterial specimens were harvested from 10 amputated lower extremities. The studies included (1) the evaluation of coaxial laser angioplasty in 10 partially or totally occluded arteries; (2) the observation of the effect of perpendicularly applied laser energy on 35 thrombi, 54 soft and 10 hard atherosclerotic, and 51 normal arterial walls; (3) the comparison of laser energy requirements for coaxial vessel lumen enlargement or recanalization vs. perpendicular penetration in 10 occluded, hard atherosclerotic arteries; and (4) the spectrographic analysis of calcium density gradient in two specimens. The results showed that the power required for vessel lumen enlargement was 10 ± 6 J/mm of atherosclerotic vessel (mean ± standard deviation). The probe followed the original arterial lumen, did not perforate the vessel wall, and created a smooth, enlarged path. The power required to penetrate perpendicularly to a similar depth for thrombi, soft and hard atherosclerotic plaques, and normal arterial walls was 15 ± 4, 30 ± 15, 65 ± 32, and 246 ± 123 J/mm, respectively. In the hard calcified specimens, laser energy required for coaxial lumen enlargement or recanalization was significantly less than that for perpendicular penetration (p <0.05), which correlated with the calcium density map indicating an increase from inside to outside. (J V ASC S URG 1987;6:60-5.)

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Web of Science research areas
Peripheral Vascular Disease
Surgery
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