Journal article
Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
International journal of environmental research and public health, v 18(22), p11824
11 Nov 2021
PMID: 34831579
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The purpose of this study was to examine the association between neighborhood social deprivation and individual-level characteristics on breast cancer staging in African American and white breast cancer patients. We established a retrospective cohort of patients with breast cancer diagnosed from 1996 to 2015 using the South Carolina Central Cancer Registry. We abstracted sociodemographic and clinical variables from the registry and linked these data to a county-level composite that captured neighborhood social conditions-the social deprivation index (SDI). Data were analyzed using chi-square tests, Student's t-test, and multivariable ordinal regression analysis to evaluate associations. The study sample included 52,803 female patients with breast cancer. Results from the multivariable ordinal regression model demonstrate that higher SDI (OR = 1.06, 95% CI: 1.02-1.10), African American race (OR = 1.35, 95% CI: 1.29-1.41), and being unmarried (OR = 1.17, 95% CI: 1.13-1.22) were associated with a distant stage at diagnosis. Higher tumor grade, younger age, and more recent year of diagnosis were also associated with distant-stage diagnosis. As a proxy for neighborhood context, the SDI can be used by cancer registries and related population-based studies to identify geographic areas that could be prioritized for cancer prevention and control efforts.
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Details
- Title
- Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina
- Creators
- Oluwole Adeyemi Babatunde - MUSC Hollings Cancer CenterWhitney E. Zahnd - University of South CarolinaJan M. Eberth - University of South CarolinaAndrew B. Lawson - Medical University of South CarolinaSwann Arp Adams - University of South CarolinaEric Adjei Boakye - Southern Illinois University School of MedicineMelanie S. Jefferson - Medical University of South CarolinaCaitlin G. Allen - Medical University of South CarolinaJohn L. Pearce - Medical University of South CarolinaHong Li - MUSC Hollings Cancer CenterChanita Hughes Halbert - University of Southern California
- Publication Details
- International journal of environmental research and public health, v 18(22), p11824
- Publisher
- Mdpi
- Number of pages
- 10
- Grant note
- R21 CA 235852 / National Cancer Institute's R21 grant R15CA179355 / National Cancer Institute's R15 grant F99 CA 222722; K00 CA 222722 / National Cancer Institute's K00 Fellowship grant
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Health Management and Policy
- Web of Science ID
- WOS:000724458000001
- Scopus ID
- 2-s2.0-85118749457
- Other Identifier
- 991021855176804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health