Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Association of Ventilation during Initial Trauma Resuscitation for Traumatic Brain Injury and Post-Traumatic Outcomes: A Systematic Review
Prehospital and disaster medicine, v 36(4), pp 460-465
01 Aug 2021
PMID: 34057405
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives: In the absence of evidence of acute cerebral herniation, normal ventilation is recommended for patients with traumatic brain injury (TBI). Despite this recommendation, ventilation strategies vary during the initial management of patients with TBI and may impact outcome. The goal of this systematic review was to define the best evidence-based practice of ventilation management during the initial resuscitation period. Methods: A literature search of PubMed, CINAHL, and SCOPUS identified studies from 2009 through 2019 addressing the effects of ventilation during the initial post-trauma resuscitation on patient outcomes. Results: The initial search yielded 899 articles, from which 13 were relevant and selected for full-text review. Six of the 13 articles met the inclusion criteria, all of which reported on patients with TBI. Either end-tidal carbon dioxide (ETCO2) or partial pressure carbon dioxide (PCO2) were the independent variables associated with mortality. Decreased rates of mortality were reported in patients with normal PCO2 or ETCO2. Conclusions: Normoventilation, as measured by ETCO2 or PCO2, is associated with decreased mortality in patients with TBI. Preventing hyperventilation or hypoventilation in patients with TBI during the early resuscitation phase could improve outcome after TBI.
Metrics
Details
- Title
- Association of Ventilation during Initial Trauma Resuscitation for Traumatic Brain Injury and Post-Traumatic Outcomes: A Systematic Review
- Creators
- Mary Beth Howard - Division of Emergency Medicine, Children's National Hospital, Washington, DCUSA.Nichole McCollum - National HospitalEmily C. Alberto - Children’s National Health SystemHannah Kotler - National Children's BureauMary E. Mottla - Children’s National Health SystemLaura Tiusaba - National HospitalSusan Keller - Children’s NationalIvan Marsic - Rutgers, The State University of New JerseyAleksandra Sarcevic - Drexel UniversityRandall S. Burd - National HospitalKaren J. O'Connell - National Hospital
- Publication Details
- Prehospital and disaster medicine, v 36(4), pp 460-465
- Publisher
- Cambridge Univ Press
- Number of pages
- 6
- Grant note
- R01LM011834 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Information Science
- Web of Science ID
- WOS:000674922300019
- Scopus ID
- 2-s2.0-85107342583
- Other Identifier
- 991019168604404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Emergency Medicine