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Association of long-term exposure to local industry- and traffic-specific particulate matter with arterial blood pressure and incident hypertension
Journal article   Peer reviewed

Association of long-term exposure to local industry- and traffic-specific particulate matter with arterial blood pressure and incident hypertension

Kateryna B. Fuks, Gudrun Weinmayr, Frauke Hennig, Lilian Tzivian, Susanne Moebus, Hermann Jakobs, Michael Memmesheimer, Hagen Kälsch, Silke Andrich, Michael Nonnemacher, …
International journal of hygiene and environmental health, v 219(6), pp 527-535
Aug 2016
DOI: https://doi.org/10.1016/j.ijheh.2016.05.008
PMID: 27318724
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Blood pressure Hypertension Industrial emissions Particulate matter Source-specific air pollution Traffic emissions
Long-term exposure to fine particulate matter (PM2.5) may lead to increased blood pressure (BP). The role of industry- and traffic-specific PM2.5 remains unclear. We investigated the associations of residential long-term source-specific PM2.5 exposure with arterial BP and incident hypertension in the population-based Heinz Nixdorf Recall cohort study. We defined hypertension as systolic BP≥140mmHg, or diastolic BP≥90mmHg, or current use of BP lowering medication. Long-term concentrations of PM2.5 from all local sources (PM2.5ALL), local industry (PM2.5IND) and traffic (PM2.5TRA) were modeled with a dispersion and chemistry transport model (EURAD-CTM) with a 1km2 resolution. We performed a cross-sectional analysis with BP and prevalent hypertension at baseline, using linear and logistic regression, respectively, and a longitudinal analysis with incident hypertension at 5-year follow-up, using Poisson regression with robust variance estimation. We adjusted for age, sex, body mass index, lifestyle, education, and major road proximity. Change in BP (mmHg), odds ratio (OR) and relative risk (RR) for hypertension were calculated per 1μg/m3 of exposure concentration. PM2.5ALL was highly correlated with PM2.5IND (Spearman’s ρ=0.92) and moderately with PM2.5TRA (ρ=0.42). In adjusted cross-sectional analysis with 4539 participants, we found positive associations of PM2.5ALL with systolic (0.42 [95%-CI: 0.03, 0.80]) and diastolic (0.25 [0.04, 0.46]) BP. Higher, but less precise estimates were found for PM2.5IND (systolic: 0.55 [−0.05, 1.14]; diastolic: 0.35 [0.03, 0.67]) and PM2.5TRA (systolic: 0.88 [−1.55, 3.31]; diastolic: 0.41 [−0.91, 1.73]). We found crude positive association of PM2.5TRA with prevalence (OR 1.41 [1.10, 1.80]) and incidence of hypertension (RR 1.38 [1.03, 1.85]), attenuating after adjustment (OR 1.19 [0.90, 1.58] and RR 1.28 [0.94, 1.72]). We found no association of PM2.5ALL and PM2.5IND with hypertension. Long-term exposures to all-source and industry-specific PM2.5 were positively related to BP. We could not separate the effects of industry-specific PM2.5 from all-source PM2.5. Estimates with traffic-specific PM2.5 were generally higher but inconclusive.

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19 citations in Web of Science
41 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being
#11 Sustainable Cities and Communities

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Collaboration types
Domestic collaboration
Web of Science research areas
Infectious Diseases
Public, Environmental & Occupational Health
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